Indiana dominated Oregon 56-22 in a stunning performance at Mercedes-Benz Stadium, with quarterback Fernando Mendoza throwing five touchdown passes to five different receivers. The Hoosiers seized control early when D'Angelo Ponds returned an interception 25 yards for a score just 1:12 into the game, sparking a relentless offensive attack that saw Indiana score 35 unanswered points to build a commanding 42-7 lead. Kaelon Black added two rushing touchdowns as the Hoosiers rolled to an emphatic victory.