South Florida dominated Rice in a 52-3 blowout at Raymond James Stadium, fueled by Byrum Brown's spectacular five-touchdown performance. Brown threw for four scores—including two to Keshaun Singleton—and added a rushing touchdown to power the Bulls' relentless offensive attack. The Bulls' defense stifled the Owls throughout the contest, allowing just a single field goal by Enock Gota as time expired in the first half.