Louisville stormed back from a 17-point first quarter deficit to stun Pittsburgh 34-27 at Acrisure Stadium. Miller Moss led the Cardinals' comeback with four total touchdowns, including three crucial second-half scoring passes. The Panthers jumped out early behind Holstein's two touchdown passes and a 75-yard interception return from Rasheem Biles, but were held scoreless in the entire second half as Louisville rallied with 17 unanswered points.