James Madison dominated Weber State 45-10 in a season-opening rout at Bridgeforth Stadium, powered by a balanced offensive attack that featured four rushing touchdowns. The Dukes jumped out to a commanding 28-0 lead before halftime, with Alonza Barnett III and Matthew Sluka each accounting for two scores. Wayne Knight broke loose for a 59-yard touchdown run early in the fourth quarter as James Madison's offense proved unstoppable, scoring in every quarter of the lopsided victory.