Southeast Missouri State vs Iowa State

Iowa State made a statement at Jack Trice Stadium, rolling past Southeast Missouri State 38-10 in dominant fashion. The Cyclones controlled the game from start to finish, showcasing the kind of Big 12 power that left the visiting Redhawks searching for answers all afternoon. With 165 plays of action, Iowa State's offense found its rhythm early and never let up, building a commanding lead that put this one away well before the final whistle. The Redhawks managed just 10 points against a swarming Cyclones defense that set the tone in Ames. Iowa State moves forward with momentum, while Southeast Missouri State heads home with a tough lesson learned against FBS competition.